Summary: Unsatisfied kinetochore-microtubule attachment activates the spindle assembly checkpoint to inhibit the metaphase-anaphase transition.However, some cells eventually override mitotic arrest by mitotic slippage.Here, we show that inactivation of TORC1 kinase elicits mitotic slippage in budding yeast and human cells.Yeast mitotic slippage was
IntroductionThe seeds of many plants are dormant and unable to germinate at maturity, but gain the ability to germinate through after-ripening during dry storage.The hormone abscisic acid (ABA) stimulates seed dormancy, whereas toyo proxes st iii 305/40r22 gibberellin A (GA) stimulates dormancy loss and germination.MethodsTo determine whether dry a
To produce bioethanol from model cyanobacteria such as Synechocystis, a two gene cassette consisting of genes encoding pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) flying cross soft shell jacket are required to transform pyruvate first to acetaldehyde and then to ethanol.However the partition of pyruvate to ethanol comes at a cost,
A novel approach, designated as the particle-mediated, nano-scale, aggregation route, to the formation and growth of spherical and colloid-sized anhydrous carbonate mineral particles and hierarchically organized biomineral carbonate structures is discussed.This model is inconsistent with the conventional crystallization mechanism, which is primaril
Background Early diagnosis of head and neck cancer (HNC) will improve patient outcomes.The low incidence of HNC renders its detection 75 corvette door panels challenging for a general practitioner (GP) in primary health care (PHC).Patients and methods To examine these challenges, our cohort consisted of all patients visiting PHC centres in the City